HitPredict

Interactor 1: DSH (P51140)
Segment polarity protein dishevelled
Gene: DSH

Interactor 2: Q8IPP3 (Q8IPP3)
Canoe, isoform D
Gene: cno

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.800

Property	Details
Experiments	17183697, 23868974
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0007391 - dorsal closure GO:0019904 - protein domain specific binding GO:0048730 - epidermis morphogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 623 Dm			1 1817
+	Hs
		876372 DLG1_HUMAN (30-615): 4.97e-67: 237: 14.43		AFAD_HUMAN (1-1703): 0: 776: 32.18
+	Dm
		844348 DSH_DROME (1-623): 5.51e-152: 453: 100.00		Q24279_DROME (654-1320): 1.18e-99: 359: 70.92
+	Dm
		113131 DSH_DROME (1-623): 5.51e-152: 453: 100.00		M9NFI9_DROME (995-1169): 2.48e-29: 130: 27.53
+	Hs
		1021567 DLG1_HUMAN (30-615): 4.97e-67: 237: 14.43		KI13B_HUMAN (189-705): 1.02e-63: 243: 14.95
+	Hs
		151114 DVL2_HUMAN (10-613): 5.94e-110: 348: 42.23		DLG3_HUMAN (1011-1256): 1.19e-17: 91.8: 22.26
+	Mm
		1164021 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		NEB2_MOUSE (995-1109): 2.67e-30: 132: 37.82
+	Hs
		1021501 DLG2_HUMAN (43-615): 1.36e-77: 265: 13.74		DLG1_HUMAN (890-1103): 2.52e-25: 116: 18.81
+	Mm
		1163969 DLG1_MOUSE (30-615): 5.35e-70: 245: 13.93		NEB2_MOUSE (995-1109): 2.67e-30: 132: 37.82
+	Mm
		936188 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		DLG3_MOUSE (1011-1256): 1.34e-17: 91.4: 22.26
+	Mm
		1143467 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		DLG4_MOUSE (1002-1100): 1.13e-16: 88.3: 32.32
+	Hs
		1077285 DLG2_HUMAN (43-615): 1.36e-77: 265: 13.74		DLG3_HUMAN (1011-1256): 1.19e-17: 91.8: 22.26
+	Ce
		105565 Q18239_CAEEL (10-496): 3.25e-77: 262: 30.62		DLG1_CAEEL (1009-1096): 4.99e-18: 92.9: 33.33
+	Hs
		942349 DLG2_HUMAN (43-615): 1.36e-77: 265: 13.74		DLG4_HUMAN (1002-1100): 1.13e-16: 88.3: 32.32
+	Hs
		1021482 DLG1_HUMAN (30-615): 4.97e-67: 237: 14.43		DLG1_HUMAN (890-1103): 2.52e-25: 116: 18.81
+	Rn
		1144014 DLG2_RAT (43-615): 1.61e-79: 270: 13.41		DLG1_RAT (975-1100): 4.72e-12: 73.3: 23.81
+	Mm
		1143387 DLG1_MOUSE (30-615): 5.35e-70: 245: 13.93		DLG4_MOUSE (1002-1100): 1.13e-16: 88.3: 32.32
+	Hs
		1021542 DLG1_HUMAN (30-615): 4.97e-67: 237: 14.43		DLG3_HUMAN (1011-1256): 1.19e-17: 91.8: 22.26
+	Rn
		1144010 DLG1_RAT (30-615): 8.3e-64: 228: 13.60		DLG3_RAT (1011-1256): 1.2e-17: 91.8: 22.26
+	Rn
		677787 DLG1_RAT (30-615): 8.3e-64: 228: 13.60		DLG4_RAT (1002-1100): 1.13e-16: 88.3: 32.32