HitPredict

Interactor 1: DSH (P51140)
Segment polarity protein dishevelled
Gene: DSH

Interactor 2: FRIZ4 (Q9NBW1)
Frizzled-4 (dFz4)
Gene: fz4

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12958364
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0060070 - canonical Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 Dm			1 705
+	Dm
		844396 DSH_DROME (1-623): 5.51e-152: 453: 100.00		FRIZ2_DROME (25-567): 0: 572: 22.24
+	Hs
		150657 DVL1_HUMAN (10-609): 1.3e-116: 364: 41.86		FZD7_HUMAN (31-569): 0: 642: 24.09
+	Dm
		577519 DSH_DROME (1-623): 5.51e-152: 453: 100.00		FRIZ_DROME (25-571): 0: 528: 23.51
+	Hs
		150979 DVL2_HUMAN (10-613): 5.94e-110: 348: 42.23		FZD5_HUMAN (46-620): 0: 619: 24.30
+	Hs
		1273637 DVL3_HUMAN (10-615): 3.45e-110: 348: 41.81		FZD8_HUMAN (45-559): 0: 569: 21.68
+	Mm
		1142153 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		FZD7_MOUSE (28-569): 0: 645: 23.70
+	Mm
		250811 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		FZD1_MOUSE (32-568): 0: 634: 24.23
+	Mm
		1142152 DLG1_MOUSE (30-615): 5.35e-70: 245: 13.93		FZD7_MOUSE (28-569): 0: 645: 23.70
+	Mm
		250810 DLG1_MOUSE (30-615): 5.35e-70: 245: 13.93		FZD1_MOUSE (32-568): 0: 634: 24.23
+	Mm
		1142148 DLG2_MOUSE (43-615): 2.49e-79: 270: 13.41		FZD4_MOUSE (44-571): 0: 591: 32.51
+	Mm
		1142150 DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13		FZD7_MOUSE (28-569): 0: 645: 23.70
+	Hs
		254162 DLG4_HUMAN (101-615): 8.81e-58: 208: 12.74		FZD7_HUMAN (31-569): 0: 642: 24.09
+	Hs
		942398 DLG4_HUMAN (101-615): 8.81e-58: 208: 12.74		FZD1_HUMAN (32-568): 0: 637: 23.88
+	Mm
		250809 DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13		FZD1_MOUSE (32-568): 0: 634: 24.23
+	Mm
		1143526 DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13		FZD2_MOUSE (33-568): 0: 632: 24.17
+	Hs
		942341 DLG4_HUMAN (101-615): 8.81e-58: 208: 12.74		FZD2_HUMAN (33-568): 0: 632: 24.17
+	Mm
		1142147 DLG1_MOUSE (30-615): 5.35e-70: 245: 13.93		FZD4_MOUSE (44-571): 0: 591: 32.51
+	Mm
		1142145 DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13		FZD4_MOUSE (44-571): 0: 591: 32.51
+	Hs
		942397 DLG4_HUMAN (101-615): 8.81e-58: 208: 12.74		FZD4_HUMAN (44-571): 0: 590: 32.45
+	Hs
		1357060 PZRN3_HUMAN (141-617): 6.33e-38: 152: 12.00		FZD4_HUMAN (44-571): 0: 590: 32.45