HitPredict

Interactor 1: DSH (P51140)
Segment polarity protein dishevelled
Gene: DSH

Interactor 2: NKD (Q9VVV9)
Protein naked cuticle (dNkd)
Gene: NKD

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	11274052, 11356022, 18423435, 12354775, 16849595
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007367 - segment polarity determination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 623 Dm			1 928
+	Mm
		844431 DVL1_MOUSE (10-619): 3.83e-119: 371: 41.37		NKD2_MOUSE (170-254): 3.3e-30: 127: 38.82
+	Mm
		844433 DVL1_MOUSE (10-619): 3.83e-119: 371: 41.37		NKD1_MOUSE (170-257): 4.29e-30: 127: 38.64
+	Hs
		150740 DVL1_HUMAN (10-609): 1.3e-116: 364: 41.86		NKD2_HUMAN (171-258): 6.78e-31: 129: 39.77
+	Hs
		150741 DVL1_HUMAN (10-609): 1.3e-116: 364: 41.86		NKD1_HUMAN (170-257): 1.83e-29: 125: 36.36
+	Mm
		1142093 DVL3_MOUSE (10-615): 1.77e-110: 349: 41.97		NKD2_MOUSE (170-254): 3.3e-30: 127: 38.82
+	Mm
		1142095 DVL3_MOUSE (10-615): 1.77e-110: 349: 41.97		NKD1_MOUSE (170-257): 4.29e-30: 127: 38.64
+	Mm
		1141506 DVL2_MOUSE (10-604): 7.4e-109: 346: 42.04		NKD2_MOUSE (170-254): 3.3e-30: 127: 38.82
+	Mm
		1141508 DVL2_MOUSE (10-604): 7.4e-109: 346: 42.04		NKD1_MOUSE (170-257): 4.29e-30: 127: 38.64
+	Hs
		1273595 DVL3_HUMAN (10-615): 3.45e-110: 348: 41.81		NKD1_HUMAN (170-257): 1.83e-29: 125: 36.36
+	Dr
		60241 F1QNA4_DANRE (10-614): 4.91e-116: 364: 43.34		NKD2_DANRE (171-255): 1.14e-22: 103: 33.33