HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005811 - lipid droplet GO:0005886 - plasma membrane GO:0035577 - azurophil granule membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 602
+	Hs
		592222 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		914027 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		148636 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Zm
		14343 B4FNJ6_MAIZE (23-216): 1.52e-97: 284: 40.20		A0A1D6G388_MAIZE (280-589): 2.92e-13: 75.4: 13.51
+	Hs
		149274 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		148389 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		914124 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		MRCKA_HUMAN (127-469): 7.43e-16: 83.8: 12.89
+	Hs
		918914 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		895362 RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		1079932 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Dm
		185621 RAB6_DROME (16-212): 3.61e-51: 166: 41.12		MYSN_DROME (4-602): 2.13e-21: 101: 10.36