HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: TGFA1 (Q8WUH2)
Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1)
Gene: TGFBRAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25266290
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 860
+	Dm
		1097257 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		VPS18_DROME (248-859): 5.46e-101: 338: 13.64
+	Hs
		592546 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		VPS18_HUMAN (248-845): 2.73e-108: 357: 12.19
+	Hs
		914418 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		VPS18_HUMAN (248-845): 2.73e-108: 357: 12.19
+	Hs
		592486 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		VPS11_HUMAN (23-854): 1.56e-92: 314: 12.50
+	Hs
		914349 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		VPS11_HUMAN (23-854): 1.56e-92: 314: 12.50
+	Dm
		669604 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		CLH_DROME (252-801): 1.66e-74: 268: 11.52
+	Hs
		914013 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CLH1_HUMAN (260-808): 2.51e-82: 291: 11.54
+	Hs
		960817 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		CLH1_HUMAN (260-808): 2.51e-82: 291: 11.54
+	Dm
		185473 O18332_DROME (12-214): 8.93e-91: 266: 39.22		CLH_DROME (252-801): 1.66e-74: 268: 11.52
+	Hs
		914124 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		MRCKA_HUMAN (17-360): 4.26e-62: 231: 11.08
+	Sc
		619690 VPS21_YEAST (19-215): 9.7e-64: 198: 54.15		VPS3_YEAST (28-800): 9.9e-79: 277: 14.25
+	At
		1012741 RABF1_ARATH (11-189): 4.1e-67: 206: 56.67		CLAH2_ARATH (231-806): 2.41e-72: 262: 10.93
+	Sc
		619691 YPT52_YEAST (21-215): 1.67e-57: 183: 47.41		VPS3_YEAST (28-800): 9.9e-79: 277: 14.25
+	Sc
		653801 YPT52_YEAST (21-215): 1.67e-57: 183: 47.41		PEP3_YEAST (252-853): 7.36e-75: 264: 12.93
+	Sc
		731206 VPS21_YEAST (19-215): 9.7e-64: 198: 54.15		VAM6_YEAST (431-850): 4.34e-66: 241: 19.78
+	Sc
		731236 YPT52_YEAST (21-215): 1.67e-57: 183: 47.41		VAM6_YEAST (431-850): 4.34e-66: 241: 19.78
+	Sc
		731215 YPT52_YEAST (21-215): 1.67e-57: 183: 47.41		VPS41_YEAST (296-817): 3.28e-51: 196: 12.68
+	Hs
		148636 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		CTRO_HUMAN (53-277): 1.5e-10: 67.6: 14.23
+	Hs
		149274 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		CTRO_HUMAN (53-277): 1.5e-10: 67.6: 14.23
+	Hs
		148389 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CTRO_HUMAN (53-277): 1.5e-10: 67.6: 14.23