HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: SCFD1 (Q8WVM8)
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Gene: SCFD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 642
+	Hs
		918918 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		1261629 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		592403 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		914248 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		844760 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Dm
		1358720 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		Q9VHB5_DROME (37-636): 2.91e-145: 435: 21.08
+	Hs
		592522 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		914386 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		592427 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		VP33A_HUMAN (4-638): 3.25e-123: 379: 15.52
+	Dm
		1358761 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		VP33A_DROME (13-638): 7.51e-107: 337: 15.11
+	Hs
		914348 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		VP33B_HUMAN (3-639): 2.08e-111: 349: 13.40
+	Mm
		886259 RB11A_MOUSE (12-216): 7.61e-88: 259: 39.25		VP33B_MOUSE (3-639): 8.14e-106: 335: 13.26