HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: OSB11 (Q9BXB4)
Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)
Gene: OSBPL11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 747
+	Hs
		592470 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		OSB11_HUMAN (1-747): 0: 707: 100.00
+	Hs
		914325 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		OSB11_HUMAN (1-747): 0: 707: 100.00
+	Hs
		592471 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		OSB10_HUMAN (12-739): 0: 628: 54.85
+	Hs
		914326 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		OSB10_HUMAN (12-739): 0: 628: 54.85
+	Hs
		844697 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		592450 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		914300 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		844716 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Hs
		592475 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Hs
		914333 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Dm
		90638 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		E1JH23_DROME (285-686): 1.36e-121: 371: 39.57
+	Dm
		1358753 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		Q9W0K9_DROME (63-283): 1.11e-30: 122: 33.76