HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005768 - endosome GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 224
+	Hs
		1328142 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		844680 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		844649 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		1079965 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		592401 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		914246 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		1291671 RAB17_HUMAN (10-216): 1.19e-54: 175: 44.71		CHMP6_HUMAN (4-204): 2.71e-28: 107: 20.30