HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: CHM2B (Q9UQN3)
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)
Gene: CHMP2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 213
+	Hs
		208823 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHM2A_HUMAN (3-188): 3.82e-37: 130: 32.80
+	Hs
		844680 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHM4C_HUMAN (7-198): 1.36e-31: 116: 17.19
+	Hs
		208828 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CHM2A_HUMAN (3-188): 3.82e-37: 130: 32.80
+	Hs
		844735 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHM4B_HUMAN (12-200): 2.69e-30: 112: 21.03
+	Hs
		844754 RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00		CHM1A_HUMAN (14-210): 2.22e-30: 112: 17.26
+	Hs
		914165 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CHM1B_HUMAN (14-210): 7.73e-34: 121: 18.27
+	Hs
		1328142 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		CHM4B_HUMAN (12-200): 2.69e-30: 112: 21.03
+	Hs
		914481 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CHMP3_HUMAN (1-211): 2.52e-32: 118: 25.23
+	Hs
		1079965 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		CHM4B_HUMAN (12-200): 2.69e-30: 112: 21.03