HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34432599
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015031 - protein transport GO:0030667 - secretory granule membrane GO:0030672 - synaptic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 116
+	Hs
		844828 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		918878 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		1079428 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		850554 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261649 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		263199 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180836 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		844945 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		913996 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		845212 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		263215 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180855 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		914092 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		894738 RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		914322 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		845416 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		87580 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		C9JXZ5_HUMAN (46-99): 8.01e-21: 80.9: 37.04
+	Hs
		261644 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		263200 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180837 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69