HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34079125, 26496610, 34432599
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005811 - lipid droplet GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 602
+	Hs
		914027 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Dm
		284076 RAB7_DROME (1-207): 1.45e-95: 278: 76.33		MYSN_DROME (4-602): 2.13e-21: 101: 10.36
+	Hs
		845450 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		148636 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		149274 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		844984 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		MRCKA_HUMAN (127-469): 7.43e-16: 83.8: 12.89
+	Hs
		914124 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		MRCKA_HUMAN (127-469): 7.43e-16: 83.8: 12.89
+	Sc
		350851 YPT1_YEAST (1-206): 8.02e-81: 241: 31.91		USO1_YEAST (128-596): 3.39e-14: 78.5: 16.00
+	Hs
		918914 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		844978 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		FKB15_HUMAN (281-582): 9.2e-12: 70.4: 11.92
+	Hs
		845205 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		FYCO1_HUMAN (130-602): 7.66e-11: 67.5: 21.11
+	Hs
		845035 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		894756 RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		844496 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		149150 RAB7B_HUMAN (1-192): 8.65e-61: 190: 50.00		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		845527 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		FKB15_HUMAN (281-582): 9.2e-12: 70.4: 11.92
+	Hs
		845697 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		FYCO1_HUMAN (130-602): 7.66e-11: 67.5: 21.11
+	Hs
		845573 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20
+	Hs
		148551 RAB13_HUMAN (8-174): 6.65e-37: 129: 38.32		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03