HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: FLOT2 (Q14254)
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)
Gene: FLOT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34432599
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 428
+	Hs
		914069 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		845477 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		279484 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279502 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		844518 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		279483 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Dm
		284092 RAB7_DROME (1-207): 1.45e-95: 278: 76.33		Q9VWL0_DROME (4-231): 8.87e-33: 128: 17.54
+	Dm
		185509 O18332_DROME (2-206): 2.18e-83: 247: 32.68		Q9VWL0_DROME (4-231): 8.87e-33: 128: 17.54
+	Hs
		646145 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646158 RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		73285 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		B4E2V5_HUMAN (4-231): 1.93e-33: 127: 16.59
+	Hs
		845337 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90
+	Hs
		844788 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90