Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: PA1B2 (P68402)
Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta)
Gene: PAFAH1B2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 10727864, 33961781, 38334954, 27173435, 37689310, 19622634, 12885786
Identification Methods pull down, affinity chromatography technology, cross-linking study, two hybrid, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Lipase_GDSL_2~WD40
Common GO terms GO:0005829 - cytosol
GO:0008247 - 1-alkyl-2-acetylglycerophosphocholine esterase complex
GO:0016042 - lipid catabolic process
GO:0046982 - protein heterodimerization activity
GO:0070062 - extracellular exosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 410
Hs

1 229
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025