HitPredict

Interactor 1: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Interactor 2: BIG3 (Q5TH69)
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)
Gene: ARFGEF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 2177
+	Hs
		1070237 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		BIG3_HUMAN (1-2177): 0: 2853: 100.00
+	Hs
		844982 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		BIG3_HUMAN (1-2177): 0: 2853: 100.00
+	Hs
		845394 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		845835 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		1070486 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Hs
		845393 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Hs
		845834 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Hs
		914499 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		914498 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Sc
		350838 YPT1_YEAST (2-201): 4.07e-74: 223: 33.97		SEC7_YEAST (600-1911): 0: 760: 13.78
+	Sc
		502989 YPT31_YEAST (7-172): 4.28e-37: 130: 40.12		SEC7_YEAST (600-1911): 0: 760: 13.78
+	Hs
		845119 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		894784 RAB8A_HUMAN (1-199): 2.22e-76: 229: 35.12		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		914254 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Sc
		350883 YPT1_YEAST (2-201): 4.07e-74: 223: 33.97		GEA2_YEAST (605-1125): 1.16e-98: 353: 12.34
+	Sc
		350894 YPT1_YEAST (2-201): 4.07e-74: 223: 33.97		GEA1_YEAST (593-1146): 4.41e-90: 326: 11.88
+	Hs
		1070421 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		PSD3_HUMAN (620-936): 1.67e-64: 242: 13.13
+	Hs
		914406 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		PSD3_HUMAN (620-936): 1.67e-64: 242: 13.13
+	Dm
		53567 O18332_DROME (2-201): 1.97e-76: 229: 32.84		A1Z8W9_DROME (1337-1636): 3.95e-53: 209: 11.82