HitPredict

Interactor 1: PLCD1 (P51178)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)
Gene: PLCD1

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH_12~Ras
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 756 Hs			1 218
+	Hs
		914080 PLCB4_HUMAN (16-755): 0: 722: 29.80		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		884491 PLCB4_HUMAN (16-755): 0: 722: 29.80		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		895288 PLCB1_HUMAN (9-756): 0: 708: 29.07		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	At
		1107294 PLCD9_ARATH (219-753): 2.55e-142: 430: 24.55		RAA1B_ARATH (5-217): 5.47e-84: 250: 66.67
+	Hs
		580971 PLCG1_HUMAN (478-754): 4.91e-75: 266: 36.56		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		895108 PLCH1_HUMAN (438-756): 1.24e-73: 263: 37.77		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56