HitPredict

Interactor 1: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1590 Hs			1 127
+	Hs
		846736 SMCA2_HUMAN (1-1590): 0: 1088: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		846990 SMCA4_HUMAN (40-1588): 0: 977: 72.70		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		846915 SMCA4_HUMAN (40-1588): 0: 977: 72.70		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		229415 SMCA5_HUMAN (610-1584): 0: 803: 27.43		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		229321 SMCA5_HUMAN (610-1584): 0: 803: 27.43		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		229353 SMCA5_HUMAN (610-1584): 0: 803: 27.43		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		229458 SMCA5_HUMAN (610-1584): 0: 803: 27.43		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		658684 SMCA1_HUMAN (618-1559): 0: 797: 28.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		658646 SMCA1_HUMAN (618-1559): 0: 797: 28.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1059648 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		1059777 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		241527 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		707635 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		886109 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		918368 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1059782 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1059827 CHD4_HUMAN (370-1589): 0: 749: 22.31		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		707755 CHD8_HUMAN (19-1359): 0: 741: 21.67		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		918705 CHD8_HUMAN (19-1359): 0: 741: 21.67		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Sc
		356040 ISW2_YEAST (537-1576): 0: 765: 24.75		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36