HitPredict - High confidence protein-protein interactions

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: SNF5 (Q12824)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (BRG1-associated factor 47) (BAF47) (Integrase interactor 1 protein) (SNF5 homolog) (hSNF5)
Gene: SMARCB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.98	0.60	0.769

Property	Details
Experiments	23602572, 11238380, 8895581, 29374058, 24981860, 33961781, 34591612, 18809673, 18414052, 15150092, 9744861, 20506188, 16687403, 30962207, 11726552, 9845365, 31043422, 19448667, 35271311, 35235311 and 15 others more... 14559996, 16287714, 18042045, 9584200, 20460684, 21520050, 22573825, 19164553, 22140357, 30108113, 31759698, 23540691, 10078207, 12368262, 15985610
Identification Methods	affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down, tandem affinity purification, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000785 - chromatin GO:0001188 - RNA polymerase I preinitiation complex assembly GO:0001650 - fibrillar center GO:0002039 - p53 binding and 32 others more... GO:0003677 - DNA binding GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006337 - nucleosome disassembly GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II GO:0007399 - nervous system development GO:0016363 - nuclear matrix GO:0016514 - SWI/SNF complex GO:0016586 - RSC-type complex GO:0030071 - regulation of mitotic metaphase/anaphase transition GO:0030957 - Tat protein binding GO:0032991 - protein-containing complex GO:0043923 - positive regulation by host of viral transcription GO:0045582 - positive regulation of T cell differentiation GO:0045597 - positive regulation of cell differentiation GO:0045663 - positive regulation of myoblast differentiation GO:0045815 - transcription initiation-coupled chromatin remodeling GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051091 - positive regulation of DNA-binding transcription factor activity GO:0070316 - regulation of G0 to G1 transition GO:0071564 - npBAF complex GO:0071565 - nBAF complex GO:0140092 - bBAF complex GO:1901838 - positive regulation of transcription of nucleolar large rRNA by RNA polymerase I GO:1902459 - positive regulation of stem cell population maintenance GO:1902661 - positive regulation of glucose mediated signaling pathway GO:2000045 - regulation of G1/S transition of mitotic cell cycle GO:2000781 - positive regulation of double-strand break repair GO:2000819 - regulation of nucleotide-excision repair
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	1647
Hs

1	385

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024