HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: BCL7A (Q4VC05)
B-cell CLL/lymphoma 7 protein family member A
Gene: BCL7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 29374058, 31043422, 24981860, 35271311, 20460684
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II GO:0008284 - positive regulation of cell population proliferation GO:0016514 - SWI/SNF complex and 9 others more... GO:0030071 - regulation of mitotic metaphase/anaphase transition GO:0045596 - negative regulation of cell differentiation GO:0045892 - negative regulation of DNA-templated transcription GO:0070316 - regulation of G0 to G1 transition GO:0140288 - GBAF complex GO:1902459 - positive regulation of stem cell population maintenance GO:2000045 - regulation of G1/S transition of mitotic cell cycle GO:2000781 - positive regulation of double-strand break repair GO:2000819 - regulation of nucleotide-excision repair
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	1647
Hs

1	210

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024