Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.719

The method score is based on:

Property Details
Experiments 11238380, 11784859, 16800816, 14559996, 19081374
Identification Methods biochemical, affinity chromatography technology, pull down
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1647
Hs

1 1273
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024