HitPredict

Interactor 1: AFC2 (P51567)
Serine/threonine-protein kinase AFC2 (EC 2.7.12.1)
Gene: AFC2

Interactor 2: SRC33 (Q9SEU4)
Serine/arginine-rich SC35-like splicing factor SCL33 (At-SCL33) (AtSCL33) (SC35-like splicing factor 33) (Serine/arginine-rich splicing factor 33)
Gene: SCL33

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.80	0.657

Property	Details
Experiments	10593939
Identification Methods	pull down, protein kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 At			1 287
+	Hs
		833938 CLK2_HUMAN (79-427): 2.38e-115: 348: 47.29		SRS12_HUMAN (31-271): 2.74e-39: 140: 32.78
+	Hs
		834087 CLK3_HUMAN (79-424): 5.5e-111: 341: 43.97		SRS12_HUMAN (31-271): 2.74e-39: 140: 32.78
+	Hs
		833788 CLK1_HUMAN (2-427): 6.61e-112: 338: 38.46		SRS12_HUMAN (31-271): 2.74e-39: 140: 32.78
+	At
		51037 A1L4Y9_ARATH (12-425): 1.65e-129: 381: 57.59		SRC30_ARATH (38-256): 4.45e-21: 91.9: 36.07
+	At
		847175 AFC3_ARATH (12-425): 1.65e-129: 381: 57.59		SRC30_ARATH (38-256): 4.45e-21: 91.9: 36.07
+	Hs
		516362 CDK2_HUMAN (95-426): 3.9e-132: 383: 25.60		PABP1_HUMAN (28-122): 2e-19: 89.8: 24.21
+	Hs
		266941 CLK2_HUMAN (79-427): 2.38e-115: 348: 47.29		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		267037 DYRK2_HUMAN (73-426): 6.54e-113: 345: 32.24		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		266942 CLK3_HUMAN (79-424): 5.5e-111: 341: 43.97		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		266940 CLK1_HUMAN (2-427): 6.61e-112: 338: 38.46		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		267075 CLK4_HUMAN (57-424): 1.5e-111: 338: 43.24		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		516416 CLK2_HUMAN (79-427): 2.38e-115: 348: 47.29		PABP1_HUMAN (28-122): 2e-19: 89.8: 24.21
+	Hs
		834033 CLK3_HUMAN (79-424): 5.5e-111: 341: 43.97		PABP4_HUMAN (1-125): 3.39e-21: 95.2: 19.20
+	Hs
		516417 CLK3_HUMAN (79-424): 5.5e-111: 341: 43.97		PABP1_HUMAN (28-122): 2e-19: 89.8: 24.21
+	Dm
		834186 DOA_DROME (76-426): 3.83e-110: 344: 47.89		Q9V3T8_DROME (33-220): 3.57e-18: 82.2: 37.23
+	Hs
		1043996 DYR1A_HUMAN (87-425): 6.93e-52: 187: 32.51		SRS12_HUMAN (31-271): 2.74e-39: 140: 32.78
+	Hs
		266986 DYR1A_HUMAN (87-425): 6.93e-52: 187: 32.51		SRS10_HUMAN (32-264): 3.84e-33: 123: 39.83
+	Hs
		1031320 DYR1A_HUMAN (87-425): 6.93e-52: 187: 32.51		PABP4_HUMAN (1-125): 3.39e-21: 95.2: 19.20
+	Hs
		201668 DYR1A_HUMAN (87-425): 6.93e-52: 187: 32.51		MSI1H_HUMAN (21-121): 3.09e-20: 91: 30.69
+	Hs
		516508 DYR1A_HUMAN (87-425): 6.93e-52: 187: 32.51		PABP1_HUMAN (28-122): 2e-19: 89.8: 24.21