Interactor 1: BAP31 (P51572)
B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28)
Gene: BCAP31

Interactor 2: CASP8 (Q14790)
Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.706

The method score is based on:

Property Details
Experiments 9334338, 21183955, 15254227, 11917123
Identification Methods enzymatic study, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0044877 - protein-containing complex binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 246
Hs

1 479
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024