HitPredict

Interactor 1: BAP31 (P51572)
B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28)
Gene: BCAP31

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0034976 - response to endoplasmic reticulum stress GO:0044233 - mitochondria-associated endoplasmic reticulum membrane contact site GO:1904294 - positive regulation of ERAD pathway
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 280
+	Hs
		847649 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		TMX4_HUMAN (20-261): 3.55e-53: 178: 41.98
+	Hs
		847609 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		TMX3_HUMAN (6-270): 4.15e-49: 170: 15.94
+	Hs
		847633 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		ERP44_HUMAN (1-161): 1.35e-38: 141: 23.12
+	Hs
		531765 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		PDIA4_HUMAN (119-266): 7.26e-15: 76.3: 9.68
+	Hs
		847546 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		671758 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		PDIA3_HUMAN (147-256): 2.92e-14: 74.4: 12.61
+	Hs
		423181 BAP31_HUMAN (1-246): 1.22e-79: 241: 100.00		PDIA1_HUMAN (66-256): 1.82e-10: 62.8: 10.68
+	Dm
		870489 Q9W0M4_DROME (1-246): 7.91e-64: 200: 36.03		PDI_DROME (60-261): 1.05e-10: 63.6: 13.02