Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.55 0.714

The method score is based on:

Property Details
Experiments 12815053, 24835992, 14647413, 32286328, 28985013, 24448238
Identification Methods enzymatic study, pull down, affinity chromatography technology, far western blotting, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0006302 - double-strand break repair
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024