Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Interactor 2: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.997

The method score is based on:

Property Details
Experiments 26145171, 25585578, 26833090, 27941124, 18429819, 23935068, 16513631, 15065660, 24835992, 15713648, 28757209, 12941707, 11239456, 12442171, 15897881, 31113933, 9126738, 24981860, 35061896, 10551859 and 35 others

more...

Identification Methods affinity chromatography technology, pull down, x-ray crystallography, unspecified method, biochemical, two hybrid, molecular sieving, comigration in non denaturing gel electrophoresis, electrophoretic mobility shift assay, anti tag coimmunoprecipitation and 10 others

more...

Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCA2~Rad51
Common GO terms GO:0000152 - nuclear ubiquitin ligase complex
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000800 - lateral element
and 9 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 3418
Hs

1 339
+ Hs
+ Hs
+ Hs
+ Cl
+ Mm
+ Mm
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024