HitPredict

Interactor 1: HCFC1 (P51610)
Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]
Gene: HCFC1

Interactor 2: THAP7 (Q9BT49)
THAP domain-containing protein 7
Gene: THAP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2035 Hs			1 309
+	Hs
		848260 HCFC1_HUMAN (1-2035): 0: 643: 100.00		THAP6_HUMAN (1-111): 6.73e-36: 130: 31.53
+	Hs
		848270 HCFC1_HUMAN (1-2035): 0: 643: 100.00		THA11_HUMAN (1-206): 4.37e-31: 120: 22.60
+	Hs
		848289 HCFC1_HUMAN (1-2035): 0: 643: 100.00		THAP2_HUMAN (1-116): 8.18e-29: 112: 35.77
+	Hs
		848301 HCFC1_HUMAN (1-2035): 0: 643: 100.00		THAP1_HUMAN (1-102): 5.11e-29: 112: 31.37
+	Hs
		848262 HCFC1_HUMAN (1-2035): 0: 643: 100.00		THAP3_HUMAN (1-194): 5.18e-28: 110: 21.65
+	Dm
		1359883 HCF_DROME (948-2031): 9.87e-34: 144: 15.87		MBDR2_DROME (1-273): 8.18e-67: 228: 16.61
+	Hs
		1328335 HCFC2_HUMAN (1593-2009): 4.41e-38: 157: 32.51		THAP2_HUMAN (1-116): 8.18e-29: 112: 35.77
+	Hs
		1259626 HCFC2_HUMAN (1593-2009): 4.41e-38: 157: 32.51		THAP3_HUMAN (1-194): 5.18e-28: 110: 21.65