Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.578

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 712
Hs

1 653
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024