Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: PELI3 (Q8N2H9)
E3 ubiquitin-protein ligase pellino homolog 3 (Pellino-3) (EC 2.3.2.27)
Gene: PELI3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 0.60 | 0.746 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25027698, 18326498, 17675297, 12874243, 15917247, 16884718, 19081057, 17997719 |
| Identification Methods | affinity chromatography technology, pull down, protein kinase assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0045087 - innate immune response |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
