HitPredict

Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 35792897, 21903422, 15767370
Identification Methods affinity chromatography technology, pull down, fluorescent resonance energy transfer, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010008 - endosome membrane
and 3 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 712
Hs

1 503
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024