Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.758 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17276401, 16107720, 11397809, 26673132, 10854325, 17113392, 21903422, 19716405, 15388348, 16024789, 23244239, 11751856 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, in-gel kinase assay |
| Interaction Type | physical association, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0045087 - innate immune response GO:0070498 - interleukin-1-mediated signaling pathway |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
