Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21911421
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_6~Pkinase
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007249 - canonical NF-kappaB signal transduction
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 712
Hs

1 1032
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024