HitPredict - High confidence protein-protein interactions

Interactor 1: CAV2 (P51636)
Caveolin-2
Gene: CAV2

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

Property	Details
Experiments	12414992, 31980649, 9361015, 33961781, 24013648, unassigned2173, 10212252
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0001935 - endothelial cell proliferation GO:0001937 - negative regulation of endothelial cell proliferation GO:0002080 - acrosomal membrane GO:0002095 - caveolar macromolecular signaling complex and 19 others more... GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005901 - caveola GO:0005925 - focal adhesion GO:0016050 - vesicle organization GO:0019065 - receptor-mediated endocytosis of virus by host cell GO:0019901 - protein kinase binding GO:0030154 - cell differentiation GO:0030674 - protein-macromolecule adaptor activity GO:0031410 - cytoplasmic vesicle GO:0032991 - protein-containing complex GO:0042383 - sarcolemma GO:0045121 - membrane raft GO:0046982 - protein heterodimerization activity GO:0048471 - perinuclear region of cytoplasm GO:0051480 - regulation of cytosolic calcium ion concentration GO:0060090 - molecular adaptor activity GO:0070836 - caveola assembly GO:0071711 - basement membrane organization
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	162
Hs

1	178

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024