HitPredict

Interactor 1: CAV3 (P51637)
Caveolin-3 (M-caveolin)
Gene: CAV3

Interactor 2: ACTN1 (Q7TPR4)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24952909
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030018 - Z disc GO:0044325 - transmembrane transporter binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 151 Mm			1 892
+	Mm
		848587 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		ACTN4_MOUSE (11-892): 0: 607: 86.51
+	Mm
		848646 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		Q5FW75_MOUSE (11-892): 0: 607: 80.16
+	Hs
		164606 CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73		SPTN2_HUMAN (224-805): 2.91e-16: 86.3: 12.84
+	Hs
		963297 CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73		SPTB2_HUMAN (183-871): 8.53e-14: 78.2: 10.78
+	Mm
		548788 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		SPTB1_MOUSE (247-798): 8.8e-12: 71.6: 11.65
+	Mm
		848660 CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00		SPTB2_MOUSE (243-790): 1.01e-09: 64.7: 8.53