Interactor 1: ZAP70 (P43403)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70
Interactor 2: THMS1 (Q8N1K5)
Protein THEMIS (Thymocyte-expressed molecule involved in selection)
Gene: THEMIS
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.60 | 0.550 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23460737 |
| Identification Methods | pull down, protein kinase assay |
| Interaction Type | association, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002250 - adaptive immune response GO:0005737 - cytoplasm GO:0005911 - cell-cell junction GO:0050852 - T cell receptor signaling pathway |
| Homologous interactions | 1 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025