HitPredict

Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: PAAF1 (Q9BRP4)
Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71)
Gene: PAAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	17353931, 26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 392
+	Hs
		124920 EIF3F_HUMAN (2-279): 1.1e-98: 297: 26.88		FBXW7_HUMAN (167-390): 5.39e-51: 183: 14.98
+	Sc
		860042 RPN8_YEAST (7-322): 1.4e-99: 298: 47.01		RPN14_YEAST (111-340): 7.56e-26: 109: 30.49
+	Hs
		124819 EIF3F_HUMAN (2-279): 1.1e-98: 297: 26.88		WDR5_HUMAN (314-390): 8.57e-15: 76.6: 9.88
+	Ce
		954231 CSN5_CAEEL (7-160): 2.74e-43: 154: 17.50		LIS1_CAEEL (1-248): 8.65e-67: 218: 18.02
+	Hs
		921026 CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38		GBB1_HUMAN (6-283): 1.85e-46: 164: 19.66
+	Hs
		903414 CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38		WDR5_HUMAN (314-390): 8.57e-15: 76.6: 9.88
+	Hs
		1272699 CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38		PRP19_HUMAN (89-204): 4.23e-13: 72.4: 33.06