HitPredict

Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	14743216, 17353931
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 522
+	Hs
		124967 EIF3F_HUMAN (2-279): 1.1e-98: 297: 26.88		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		849251 PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		849266 PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Hs
		1020844 CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		177065 EIF3H_HUMAN (3-275): 1.64e-66: 214: 17.65		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Mm
		192893 PSDE_MOUSE (5-142): 6.8e-28: 112: 24.31		RO52_MOUSE (51-403): 1.44e-45: 167: 14.17