HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: MARH1 (Q8TCQ1)
E3 ubiquitin-protein ligase MARCHF1 (EC 2.3.2.27) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I) (RING finger protein 171) (RING-type E3 ubiquitin transferase MARCHF1)
Gene: MARCHF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14722266
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 289
+	Hs
		849338 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MARH8_HUMAN (13-289): 8.39e-90: 270: 65.04
+	Hs
		895806 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		MARH8_HUMAN (13-289): 8.39e-90: 270: 65.04
+	Hs
		1199325 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		919767 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		895832 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		849469 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MARH4_HUMAN (69-285): 3.34e-55: 185: 23.58
+	Hs
		849466 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MARH2_HUMAN (21-239): 4.71e-55: 180: 24.20
+	Hs
		1199317 UB2E2_HUMAN (4-146): 3.11e-74: 221: 62.94		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		851833 UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		851897 UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94		MARH2_HUMAN (21-239): 4.71e-55: 180: 24.20
+	Hs
		849461 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		919880 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		895930 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		231862 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		MARH6_HUMAN (72-228): 3.96e-33: 130: 24.56
+	Hs
		1282354 UB2E3_HUMAN (4-146): 1.2e-73: 220: 62.94		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		851894 UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		849448 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78
+	Hs
		919864 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78
+	Hs
		895915 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78
+	Hs
		851887 UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78