HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: ARRD3 (Q96B67)
Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP)
Gene: ARRDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 414
+	Hs
		919814 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Hs
		1285049 UB2E2_HUMAN (4-146): 3.11e-74: 221: 62.94		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Hs
		1282322 UB2E3_HUMAN (4-146): 1.2e-73: 220: 62.94		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Dm
		854566 UBCD2_DROME (4-146): 6.98e-74: 221: 64.34		Q8SYU5_DROME (7-413): 4.59e-103: 315: 20.43
+	Hs
		1234599 UB2E3_HUMAN (4-146): 1.2e-73: 220: 62.94		ARRD1_HUMAN (3-412): 6.67e-68: 223: 21.43
+	Hs
		851842 UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94		ARRD1_HUMAN (3-412): 6.67e-68: 223: 21.43
+	Dm
		854572 UBCD2_DROME (4-146): 6.98e-74: 221: 64.34		Q9VGU4_DROME (12-309): 4.75e-62: 210: 22.30