HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: UHRF2 (Q96PU4)
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)
Gene: UHRF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	29506131, 21952639, 14741369
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 802
+	Hs
		1299596 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		919833 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		895886 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		849419 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		919835 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		895889 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		896525 UBE2N_HUMAN (4-147): 1.92e-68: 205: 45.83		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Zm
		13330 A0A1D6FSE0_MAIZE (1-147): 1.53e-82: 241: 76.19		A0A1D6FSK8_MAIZE (419-766): 1.4e-75: 260: 17.32