Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1
Interactor 2: RN181 (Q9P0P0)
E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181)
Gene: RNF181
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.925 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18331836, 26711259, 32296183, 19690564, unassigned1304 |
| Identification Methods | pull down, two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~zf-RING_2 |
| Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm GO:0061630 - ubiquitin protein ligase activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
