HitPredict

Interactor 1: CCL11 (P51671)
Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11)
Gene: CCL11

Interactor 2: CCL14 (Q16627)
C-C motif chemokine 14 (Chemokine CC-1/CC-3) (HCC-1/HCC-3) (HCC-1(1-74)) (NCC-2) (Small-inducible cytokine A14) [Cleaved into: HCC-1(3-74); HCC-1(4-74); HCC-1(9-74)]
Gene: CCL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0002548 - monocyte chemotaxis
GO:0005615 - extracellular space
GO:0006874 - intracellular calcium ion homeostasis
GO:0006954 - inflammatory response
GO:0007186 - G protein-coupled receptor signaling pathway
and 10 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 97
Hs

1 93
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024