HitPredict

Interactor 1: CCR3 (P51677)
C-C chemokine receptor type 3 (C C CKR3) (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR 3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193)
Gene: CCR3

Interactor 2: CCL15 (Q16663)
C-C motif chemokine 15 (Chemokine CC-2) (HCC-2) (Leukotactin-1) (LKN-1) (MIP-1 delta) (Macrophage inflammatory protein 5) (MIP-5) (Mrp-2b) (NCC-3) (Small-inducible cytokine A15) [Cleaved into: CCL15(22-92); CCL15(25-92); CCL15(29-92)]
Gene: CCL15

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9346309
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 113
+	Hs
		686668 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL15_HUMAN (1-113): 1.65e-40: 131: 100.00
+	Hs
		686626 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL23_HUMAN (1-112): 2.97e-38: 126: 72.57
+	Hs
		486230 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL3_HUMAN (1-112): 8.89e-32: 109: 40.18
+	Hs
		561728 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CL3L1_HUMAN (1-112): 9.15e-32: 109: 39.29
+	Mm
		500591 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL3_MOUSE (1-112): 1.4e-30: 105: 34.82
+	Hs
		526560 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL4_HUMAN (1-111): 3.4e-30: 105: 36.04
+	Hs
		686667 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL14_HUMAN (1-111): 2.63e-30: 105: 32.14
+	Mm
		534669 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL4_MOUSE (43-111): 5.13e-26: 94.4: 44.93
+	Hs
		686635 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL8_HUMAN (44-110): 9.44e-26: 94.1: 38.24
+	Hs
		686636 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL7_HUMAN (44-112): 2.03e-25: 93.3: 35.71
+	Hs
		849723 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL18_HUMAN (1-112): 1.51e-27: 98.3: 35.71
+	Hs
		528244 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL5_HUMAN (39-111): 1.44e-23: 88.3: 34.25
+	Hs
		528201 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL2_HUMAN (44-112): 2.72e-23: 87.9: 31.43
+	Hs
		180158 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL16_HUMAN (34-107): 7.05e-23: 87.5: 28.38
+	Hs
		607526 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL1_HUMAN (1-110): 1.07e-22: 86.3: 28.18
+	Mm
		486212 CCR8_MOUSE (1-335): 1.93e-91: 279: 37.57		CCL1_MOUSE (1-110): 2.89e-19: 77.5: 27.03
+	Hs
		180162 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL16_HUMAN (34-107): 7.05e-23: 87.5: 28.38
+	Hs
		607528 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL1_HUMAN (1-110): 1.07e-22: 86.3: 28.18
+	Hs
		849725 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL17_HUMAN (43-109): 1.92e-21: 82.9: 28.36
+	Hs
		134312 ACKR4_HUMAN (10-343): 1e-85: 264: 30.09		CCL21_HUMAN (41-111): 9.71e-19: 77.1: 36.00