HitPredict

Interactor 1: CCR3 (P51677)
C-C chemokine receptor type 3 (C C CKR3) (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR 3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193)
Gene: CCR3

Interactor 2: CCL26 (Q9Y258)
C-C motif chemokine 26 (CC chemokine IMAC) (Eotaxin-3) (Macrophage inflammatory protein 4-alpha) (MIP-4-alpha) (Small-inducible cytokine A26) (Thymic stroma chemokine-1) (TSC-1)
Gene: CCL26

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	10488147
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0001938 - positive regulation of endothelial cell proliferation GO:0006935 - chemotaxis GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 94
+	Mm
		500591 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL3_MOUSE (1-91): 1.17e-31: 108: 36.96
+	Hs
		561728 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CL3L1_HUMAN (1-90): 4.71e-33: 111: 39.56
+	Hs
		486230 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL3_HUMAN (1-90): 1.5e-32: 110: 37.78
+	Hs
		526560 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL4_HUMAN (3-91): 2.29e-32: 109: 38.20
+	Mm
		534669 CCR3_MOUSE (9-355): 3.86e-90: 276: 70.03		CCL4_MOUSE (16-91): 1.79e-29: 102: 38.16
+	Hs
		686667 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL14_HUMAN (2-91): 1.23e-30: 105: 34.41
+	Hs
		686636 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL7_HUMAN (16-93): 4.4e-29: 101: 35.44
+	Hs
		686635 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL8_HUMAN (16-90): 1.05e-28: 100: 34.21
+	Hs
		528201 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL2_HUMAN (16-93): 9.59e-27: 95.8: 27.85
+	Hs
		607526 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL1_HUMAN (1-90): 2.05e-26: 94.6: 26.67
+	Hs
		849725 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL17_HUMAN (1-89): 5.64e-28: 98.9: 29.21
+	Hs
		528244 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL5_HUMAN (14-90): 3.98e-25: 91.6: 37.66
+	Hs
		686668 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL15_HUMAN (11-89): 1.75e-24: 90.4: 34.18
+	Mm
		486212 CCR8_MOUSE (1-335): 1.93e-91: 279: 37.57		CCL1_MOUSE (1-88): 3.06e-22: 84.2: 24.72
+	Hs
		849723 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL18_HUMAN (4-91): 9.96e-27: 95.4: 35.23
+	Hs
		607528 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL1_HUMAN (1-90): 2.05e-26: 94.6: 26.67
+	Hs
		686626 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL23_HUMAN (29-94): 1.6e-23: 88.1: 34.85
+	Hs
		180158 CCR1_HUMAN (1-355): 4.64e-89: 273: 62.54		CCL16_HUMAN (14-87): 9.34e-23: 86.2: 36.49
+	Hs
		180162 CCR8_HUMAN (1-338): 1.38e-86: 267: 38.60		CCL16_HUMAN (14-87): 9.34e-23: 86.2: 36.49
+	Hs
		134312 ACKR4_HUMAN (10-343): 1e-85: 264: 30.09		CCL21_HUMAN (25-91): 5.26e-17: 71.9: 28.17