HitPredict

Interactor 1: CCR5 (P51682)
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD antigen CD195)
Gene: CCR5

Interactor 2: CCL8 (Q9Z121)
C-C motif chemokine 8 (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8)
Gene: CCL8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9139699
Identification Methods	competition binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Mm			1 97
+	Mm
		486358 CCR2_MOUSE (8-354): 1.22e-85: 265: 77.81		CCL2_MOUSE (1-97): 7.15e-34: 115: 39.39
+	Hs
		849723 CCR8_HUMAN (1-350): 1.59e-91: 279: 41.43		CCL18_HUMAN (1-92): 1.74e-27: 97.3: 27.17
+	Hs
		607528 CCR8_HUMAN (1-350): 1.59e-91: 279: 41.43		CCL1_HUMAN (1-96): 3.09e-26: 94.6: 25.77
+	Hs
		486231 CXCR5_HUMAN (9-345): 1.62e-83: 259: 29.65		CCL3_HUMAN (1-92): 1.9e-32: 110: 25.81
+	Hs
		849725 CCR8_HUMAN (1-350): 1.59e-91: 279: 41.43		CCL17_HUMAN (6-89): 2.23e-23: 87.3: 29.76
+	Mm
		534670 CCR5_MOUSE (1-354): 2.35e-88: 271: 100.00		CCL4_MOUSE (1-91): 1.64e-26: 95: 30.11
+	Hs
		526561 CXCR5_HUMAN (9-345): 1.62e-83: 259: 29.65		CCL4_HUMAN (1-91): 2.97e-31: 106: 32.26
+	Mm
		849658 CCR2_MOUSE (8-354): 1.22e-85: 265: 77.81		CCL7_MOUSE (1-97): 3.04e-28: 99.6: 48.45
+	Hs
		486230 CCR1_HUMAN (14-354): 1.55e-81: 254: 56.73		CCL3_HUMAN (1-92): 1.9e-32: 110: 25.81
+	Hs
		180162 CCR8_HUMAN (1-350): 1.59e-91: 279: 41.43		CCL16_HUMAN (1-87): 1.42e-21: 83.5: 27.17
+	Hs
		526560 CCR1_HUMAN (14-354): 1.55e-81: 254: 56.73		CCL4_HUMAN (1-91): 2.97e-31: 106: 32.26
+	Hs
		528201 CCR1_HUMAN (14-354): 1.55e-81: 254: 56.73		CCL2_HUMAN (1-96): 4.18e-30: 104: 46.94
+	Hs
		528245 CXCR5_HUMAN (9-345): 1.62e-83: 259: 29.65		CCL5_HUMAN (1-90): 2.47e-24: 89.6: 31.87
+	Hs
		825305 CX3C1_HUMAN (1-348): 6.25e-83: 257: 39.60		X3CL1_HUMAN (4-93): 9.37e-22: 88.8: 27.96
+	Hs
		180159 CXCR5_HUMAN (9-345): 1.62e-83: 259: 29.65		CCL16_HUMAN (1-87): 1.42e-21: 83.5: 27.17
+	Hs
		134292 CCR7_HUMAN (2-345): 2.71e-82: 256: 33.72		CCL21_HUMAN (17-97): 1.12e-21: 84.2: 27.38
+	Hs
		180158 CCR1_HUMAN (14-354): 1.55e-81: 254: 56.73		CCL16_HUMAN (1-87): 1.42e-21: 83.5: 27.17
+	Hs
		686791 CCR7_HUMAN (2-345): 2.71e-82: 256: 33.72		CCL19_HUMAN (18-96): 5.99e-21: 81.1: 27.50
+	Hs
		127663 CCRL2_HUMAN (1-338): 2.03e-82: 255: 39.08		CCL19_HUMAN (18-96): 5.99e-21: 81.1: 27.50
+	Hs
		134725 CCR7_HUMAN (2-345): 2.71e-82: 256: 33.72		CCL22_HUMAN (18-90): 1.22e-19: 77.7: 27.40