HitPredict

Interactor 1: SPHM (P51688)
N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)
Gene: SGSH

Interactor 2: NAAA (Q02083)
N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acid ceramidase-like protein) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]
Gene: NAAA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0043202 - lysosomal lumen GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 359
+	Hs
		550462 ARSB_HUMAN (13-498): 7.44e-146: 430: 19.73		NAAA_HUMAN (1-359): 0: 534: 100.00
+	Hs
		709245 GALNS_HUMAN (5-484): 8.46e-128: 383: 21.14		NAAA_HUMAN (1-359): 0: 534: 100.00
+	Hs
		546604 ARSA_HUMAN (21-497): 1.02e-123: 372: 24.07		NAAA_HUMAN (1-359): 0: 534: 100.00
+	Hs
		968870 SULF2_HUMAN (22-425): 1.75e-116: 365: 18.58		NAAA_HUMAN (1-359): 0: 534: 100.00
+	Hs
		968859 ARSK_HUMAN (19-474): 1.85e-102: 318: 21.32		NAAA_HUMAN (1-359): 0: 534: 100.00
+	Hs
		606877 IDS_HUMAN (6-464): 8.09e-97: 305: 20.47		NAAA_HUMAN (1-359): 0: 534: 100.00