HitPredict

Interactor 1: SPHM (P51688)
N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)
Gene: SGSH

Interactor 2: SUMF1 (Q8NBK3)
Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1)
Gene: SUMF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	33961781, 15962010
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 374
+	Hs
		849866 ARSL_HUMAN (5-493): 3.49e-153: 451: 19.80		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		445230 STS_HUMAN (1-492): 5.34e-149: 440: 19.26		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		872916 ARSF_HUMAN (4-492): 3.98e-148: 438: 20.65		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		549100 GNS_HUMAN (17-490): 3.61e-130: 391: 19.35		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		709267 GALNS_HUMAN (5-484): 8.46e-128: 383: 21.14		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		546629 ARSA_HUMAN (21-497): 1.02e-123: 372: 24.07		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		1239985 ARSG_HUMAN (5-493): 1.48e-122: 370: 19.18		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		1219504 SULF2_HUMAN (22-425): 1.75e-116: 365: 18.58		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		849841 SPHM_HUMAN (1-502): 0: 527: 100.00		SUMF2_HUMAN (89-368): 1.51e-136: 393: 47.00
+	Hs
		1165653 ARSK_HUMAN (19-474): 1.85e-102: 318: 21.32		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		606914 IDS_HUMAN (6-464): 8.09e-97: 305: 20.47		SUMF1_HUMAN (1-374): 0: 598: 100.00
+	Hs
		1165652 ARSK_HUMAN (19-474): 1.85e-102: 318: 21.32		SUMF2_HUMAN (89-368): 1.51e-136: 393: 47.00
+	Hs
		606913 IDS_HUMAN (6-464): 8.09e-97: 305: 20.47		SUMF2_HUMAN (89-368): 1.51e-136: 393: 47.00