Interactor 1: STA5B (P51692)
Signal transducer and activator of transcription 5B
Gene: STAT5B

Interactor 2: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 9047382
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0005829 - cytosol
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0019221 - cytokine-mediated signaling pathway
GO:0030183 - B cell differentiation
GO:0043029 - T cell homeostasis
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024