HitPredict

Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 650 Hs			1 184
+	Mm
		925787 APLP2_MOUSE (42-648): 0: 843: 39.82		RAC1_MOUSE (1-184): 1.05e-68: 209: 27.55
+	Hs
		350102 APLP2_HUMAN (42-648): 0: 822: 35.25		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348631 APLP2_HUMAN (42-648): 0: 822: 35.25		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89
+	Mm
		517609 A4_MOUSE (23-241): 1.64e-115: 364: 42.27		RB11A_MOUSE (4-178): 2.05e-69: 211: 28.98
+	Hs
		394455 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00
+	Hs
		395730 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Hs
		394482 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		394499 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		349797 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		395561 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RIT2_HUMAN (2-178): 1.4e-54: 174: 46.89
+	Hs
		348470 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89