Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1

Interactor 2: APLP2 (Q06481)
Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II)
Gene: APLP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.681

The method score is based on:

Property Details
Experiments 16193067
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains APP_Cu_bd~APP_Cu_bd, APP_Cu_bd~APP_N, APP_E2~APP_E2, APP_N~APP_N
Common GO terms GO:0005886 - plasma membrane
GO:0007409 - axonogenesis
GO:0007417 - central nervous system development
GO:0008201 - heparin binding
GO:0046914 - transition metal ion binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 650
Hs

1 763
+ Hs
+ Mm
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+ Dm
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+ Hs

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Last updated: 15 Jul 2024