HitPredict

Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1

Interactor 2: NMDE1 (Q12879)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A) (hNR2A)
Gene: GRIN2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25683482
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 650 Hs			1 1464
+	Hs
		987500 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDE1_HUMAN (1-1464): 0: 1763: 100.00
+	Hs
		849931 APLP1_HUMAN (1-650): 0: 906: 100.00		NMDE2_HUMAN (4-1464): 0: 1550: 52.95
+	Hs
		987502 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDE2_HUMAN (4-1464): 0: 1550: 52.95
+	Hs
		394623 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDE1_HUMAN (1-1464): 0: 1763: 100.00
+	Hs
		394650 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDE2_HUMAN (4-1464): 0: 1550: 52.95
+	Hs
		849927 APLP1_HUMAN (1-650): 0: 906: 100.00		NMDZ1_HUMAN (8-940): 0: 680: 23.30
+	Rn
		70068 B1WBV6_RAT (1-650): 0: 823: 87.31		NMDZ1_RAT (8-940): 0: 685: 23.30
+	Hs
		984255 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDZ1_HUMAN (8-940): 0: 680: 23.30
+	Hs
		394583 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDZ1_HUMAN (8-940): 0: 680: 23.30