HitPredict

Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1

Interactor 2: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25683482
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 650 Hs			1 1484
+	Hs
		987502 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Hs
		849929 APLP1_HUMAN (1-650): 0: 906: 100.00		NMDE1_HUMAN (9-1484): 0: 1495: 52.39
+	Hs
		987500 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDE1_HUMAN (9-1484): 0: 1495: 52.39
+	Hs
		394650 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Hs
		394623 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDE1_HUMAN (9-1484): 0: 1495: 52.39
+	Hs
		849927 APLP1_HUMAN (1-650): 0: 906: 100.00		NMDZ1_HUMAN (13-940): 0: 668: 23.60
+	Rn
		70068 B1WBV6_RAT (1-650): 0: 823: 87.31		NMDZ1_RAT (14-940): 0: 673: 23.62
+	Hs
		984255 APLP2_HUMAN (42-648): 0: 822: 35.25		NMDZ1_HUMAN (13-940): 0: 668: 23.60
+	Hs
		394583 A4_HUMAN (41-243): 2.19e-109: 349: 42.16		NMDZ1_HUMAN (13-940): 0: 668: 23.60